Matsuoka et al., 2004

The excitation–contraction–metabolism coupling model from Matsuoka et al., 2004 is incorpolated.

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Matsuoka S, Sarai N, Jo H, Noma A.
Simulation of ATP metabolism in cardiac excitation-contraction coupling.
Prog Biophys Mol Biol. 2004 Jun-Jul;85(2-3):279-99.

  1. download simBio_*.zip and extract all.
  2. execute the simBio_*.jar included. (Java 2 Platform, Standard Edition, v 1.4.2 (J2SE) or later is needed, which is freely available from
  3. select [File]-[Open] and open xml/matsuoka_et_al_2004/exp/AnoxiaSimulation.xml.
  4. select [Model]-[Start] to simulate anoxia.


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