org.simBio.bio.kuzumoto_et_al_2007.current
Class IK1

java.lang.Object
  org.simBio.core.Component
      org.simBio.core.Parameter
          org.simBio.core.Composite
              org.simBio.core.Reactor
                  org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter
                      org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter
                          org.simBio.bio.terashima_et_al_2006.current.potassium.PureKchannel
                              org.simBio.bio.kuzumoto_et_al_2007.current.IK1

All Implemented Interfaces:

Node

public class IK1
extends PureKchannel

Inward rectifired K current, Yan and Ishihara (2005) model.

Version:

$Id: IK1.java,v 1.2 2007/12/17 07:35:14 nsarai Exp $

Author:

Keiichi Asakura

See Also:

Kuzumoto et al, 2007., "Yan DH and Ishihara K, Two Kir2.1 channel populations with different sensitivities to Mg²⁺ and polyamine block: a model for the cardiac strong inward rectifier K⁺ channel. J Physiol 563: 725-744, 2005."

Field Summary

Node	Mg the concentration of Mg2+ (mM)
double	Phi the proportion of the channels that are in the high-affinity mode (Mode1)
Node	Pspm the probability of being in the SPM block state
Node	SPM the concentration of Spermine (mM)

Fields inherited from class org.simBio.bio.terashima_et_al_2006.current.potassium.PureKchannel

Cm, permeabilityK, pOpen, reversalPotential, Vm

Fields inherited from class org.simBio.bio.terashima_et_al_2006.current.MembraneTransporter

cCl, CCl, currentCl

Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter

cCa, CCa, cK, CK, cNa, CNa, current, currentCa, currentK, currentNa, total

Fields inherited from class org.simBio.core.Parameter

value

Constructor Summary

IK1()

Method Summary

protected void

calculate(double t) add Cl current to Compartment.

Methods inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter

prepare

Methods inherited from class org.simBio.core.Composite

accept, getLink, getNode, getNodesIterator, getNodesSize

Methods inherited from class org.simBio.core.Parameter

addValue, getValue, getValueString, setInitializer, setValue, setValueString, setValueToField

Methods inherited from class org.simBio.core.Component

addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks

Methods inherited from class java.lang.Object

clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Methods inherited from interface org.simBio.core.Node

addDydt, addValue, getValue, setValue

Field Detail

Mg

public Node Mg

the concentration of Mg2+ (mM)

SPM

public Node SPM

the concentration of Spermine (mM)

Pspm

public Node Pspm

the probability of being in the SPM block state

Phi

public double Phi

the proportion of the channels that are in the high-affinity mode (Mode1)

Constructor Detail

IK1

public IK1()

Method Detail

calculate

protected void calculate(double t)

Description copied from class: MembraneTransporter

add Cl current to Compartment.

Overrides:

calculate in class PureKchannel

Parameters:

t - time

See Also:

Reactor.calculate(double)