org.simBio.bio.takeuchi_et_al_2006.current
Class INaCa

java.lang.Object
  org.simBio.core.Component
      org.simBio.core.Parameter
          org.simBio.core.Composite
              org.simBio.core.Reactor
                  org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter
                      org.simBio.bio.takeuchi_et_al_2006.current.INaCa

All Implemented Interfaces:

Node

public class INaCa
extends MembraneTransporter

Na⁺/Ca²⁺ exchanger. Two inactivation gates are incorporated according to Fujioka et al. (2000).

Version:

$Id: INaCa.java,v 1.1 2006/11/17 08:08:04 atakeuchi Exp $

Author:

Ayako Takeuchi

See Also:

"Table S10 in Takeuchi et al. 2006" "Fujioka et al. J Physiol 529: 611-623, 2000"

Field Summary

double	amplitude amplitude factor [A/F]
Node	Cai concentration of intracellular Ca2+ [mM]
Node	Cao concentration of extracellular Ca2+ [mM]
double	Cm membrane capacitance [pF]
double	F Faraday constant default value is 96.4867[C/mmol]
Node	inActivation1 I1 probability for inactivation gate 1 (Na-dependent)
Node	inActivation2 I2 probability for inactivation gate 2 (Ca-dependent)
Node	Nai concentration of intracellular Na+ [mM]
Node	Nao concentration of extracellular Na+ [mM]
Node	pE1total E1 probability
double	R gas constant default value is 8.3143[C*mV/K/mmol]
double	stoichiometryCa stoichiometry for Ca2+
double	stoichiometryNa stoichiometry for Na+
Node	T absolute temperature [K]
Node	Vm membrane potential [mV]

Fields inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter

cCa, CCa, cK, CK, cNa, CNa, current, currentCa, currentK, currentNa, total

Fields inherited from class org.simBio.core.Parameter

value

Constructor Summary

INaCa()

Method Summary

protected void

calculate(double t) add current to Compartment.

Methods inherited from class org.simBio.bio.matsuoka_et_al_2003.current.MembraneTransporter

prepare

Methods inherited from class org.simBio.core.Composite

accept, getLink, getNode, getNodesIterator, getNodesSize

Methods inherited from class org.simBio.core.Parameter

addValue, getValue, getValueString, setInitializer, setValue, setValueString, setValueToField

Methods inherited from class org.simBio.core.Component

addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks

Methods inherited from class java.lang.Object

clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Methods inherited from interface org.simBio.core.Node

addDydt, addValue, getValue, setValue

Field Detail

Nai

public Node Nai

concentration of intracellular Na⁺ [mM]

Nao

public Node Nao

concentration of extracellular Na⁺ [mM]

Cai

public Node Cai

concentration of intracellular Ca²⁺ [mM]

Cao

public Node Cao

concentration of extracellular Ca²⁺ [mM]

Vm

public Node Vm

membrane potential [mV]

inActivation1

public Node inActivation1

I1 probability for inactivation gate 1 (Na-dependent)

inActivation2

public Node inActivation2

I2 probability for inactivation gate 2 (Ca-dependent)

pE1total

public Node pE1total

E1 probability

R

public double R

gas constant default value is 8.3143[C*mV/K/mmol]

T

public Node T

absolute temperature [K]

F

public double F

Faraday constant default value is 96.4867[C/mmol]

stoichiometryNa

public double stoichiometryNa

stoichiometry for Na⁺

stoichiometryCa

public double stoichiometryCa

stoichiometry for Ca²⁺

amplitude

public double amplitude

amplitude factor [A/F]

Cm

public double Cm

membrane capacitance [pF]

Constructor Detail

INaCa

public INaCa()

Method Detail

calculate

protected void calculate(double t)

Description copied from class: MembraneTransporter

add current to Compartment.

Overrides:

calculate in class MembraneTransporter

Parameters:

t - time