org.simBio.bio.matsuoka_et_al_2004.molecule.enzyme
Class CK

java.lang.Object
  org.simBio.core.Component
      org.simBio.core.Parameter
          org.simBio.core.Composite
              org.simBio.core.Reactor
                  org.simBio.bio.matsuoka_et_al_2004.molecule.enzyme.CK

All Implemented Interfaces:

Node

public class CK
extends Reactor

Creatine Kinase (CK) System.

  vCK = kf*[ADP]total*[PhosphoCreatine]*[H+] - kb*[ATP]total*[Creatine]
 

Since:

rc20

Version:

$Id: CK.java,v 1.2 2006/05/30 07:28:50 nsarai Exp $

Author:

SAITO Ryuta

See Also:

Korzeniewski & Zoladz 2001 Korzeniewski & Zoladz 2003 Matsuoka et al. 2004
XML example explanation (Japanese, WORD doc)

Field Summary

Node	ADPtotal total ADP concentration in cytosol
Node	ATPtotal total ATP concentration in cytosol
Node	Cr creatine concentration in cytosol
double	kbCK rate constant of backward reaction of creatine kinase, (Default value: 0.00000966767)
double	kfCK rate constant of forward reaction of creatine kinase, (Default value: 16.04833)
Node	PCr phosphocreatine concentration in cytosol
Node	Proton proton concentration in cytosol

Fields inherited from class org.simBio.core.Parameter

value

Constructor Summary

CK()

Method Summary

protected void

calculate(double t) write equations here, and calculate dy over dt.

Methods inherited from class org.simBio.core.Composite

accept, getLink, getNode, getNodesIterator, getNodesSize

Methods inherited from class org.simBio.core.Parameter

addValue, getValue, getValueString, prepare, setInitializer, setValue, setValueString, setValueToField

Methods inherited from class org.simBio.core.Component

addDydt, end, getIndent, getIndentedShortName, getName, getName, getParent, getRoot, getShortName, getUnits, isNamed, isPrefixed, logIndented, quit, setLinks

Methods inherited from class java.lang.Object

clone, equals, finalize, getClass, hashCode, notify, notifyAll, toString, wait, wait, wait

Methods inherited from interface org.simBio.core.Node

addDydt, addValue, getValue, setValue

Field Detail

ATPtotal

public Node ATPtotal

total ATP concentration in cytosol

ADPtotal

public Node ADPtotal

total ADP concentration in cytosol

PCr

public Node PCr

phosphocreatine concentration in cytosol

Cr

public Node Cr

creatine concentration in cytosol

Proton

public Node Proton

proton concentration in cytosol

kfCK

public double kfCK

rate constant of forward reaction of creatine kinase, (Default value: 16.04833)

kbCK

public double kbCK

rate constant of backward reaction of creatine kinase, (Default value: 0.00000966767)

Constructor Detail

CK

public CK()

Method Detail

calculate

protected void calculate(double t)

Description copied from class: Reactor

write equations here, and calculate dy over dt.
計算中に呼び出される。 計算式を記載する。dy/dtをここで計算する。

Specified by:

calculate in class Reactor

Parameters:

t - elapsed time (ms)